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targetmol natural product databases  (TargetMol)


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    TargetMol targetmol natural product databases
    Targetmol Natural Product Databases, supplied by TargetMol, used in various techniques. Bioz Stars score: 95/100, based on 109 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/targetmol+natural+product+databases/Natural+Product+Library+for+HTS/pm40526642-300-13-13
    Average 95 stars, based on 109 article reviews
    targetmol natural product databases - by Bioz Stars, 2026-09
    95/100 stars

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    Article Title: WRN as a Novel Target of Synthetic Lethality: Current Advances and Future Perspectives.
    Article Snippet: Werner syndrome (WS) is an autosomal recessive disorder caused by mutations in the Werner syndrome protein (WRN, also known as RecQ3) gene.. As a pivotal member of the RecQ DNA helicase family, WRN facilitates essential processes in DNA replication, recombination, and repair, thus safeguarding genomic stability.. In this perspective, we provide a critical analysis of WRN’s structural and biological features as well as its regulatory networks.

    Article Title: Discovering potential WRN inhibitors from natural product database through computational methods.
    Article Snippet: Microsatellite instability (MSI) is a relatively common feature associated with multiple cancers, and Werner syndrome (WRN) ATP-dependent helicase has been recognized as a novel target for treating MSI cancers, such as colorectal cancer.. A small-molecule inhibitor targeting WRN would be a promising strategy for treating colorectal cancer with high MSI expression.. In this study, we employed a computer-assisted drug discovery strategy to screen over 30,000 natural product molecules.



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